WESSON, MS — A tragic head-on collision on Interstate 55 late Friday night has left one patient dead and two Pafford EMS crew members fighting for their lives. The accident occurred on February 6, 2026, near Wesson, when an ambulance traveling northbound was struck by an oncoming vehicle.
The impact of the crash was devastating for those inside the emergency vehicle. Pafford EMS confirmed the heartbreaking news that the patient being transported at the time of the collision was pronounced deceased at the scene. The two crew members on board sustained severe injuries and were airlifted to a regional trauma center, where they remain in critical condition. Details regarding the condition and identity of the driver in the second vehicle have not yet been released.
In a statement released following the incident, Pafford EMS expressed profound grief and called for the community to join them in prayer for all those affected. The organization emphasized that their primary focus is the recovery of their team members and providing support to their families during this difficult time. They also extended a sincere thank you to the fellow emergency responders who arrived on the scene to provide aid to the four individuals involved.
The Mississippi Highway Patrol is currently the lead agency investigating the crash. While the specific circumstances leading up to the head-on impact remain unclear, investigators are working to determine how the collision occurred on the busy interstate. Pafford EMS noted that the information remains preliminary and that they will provide further updates as more details are confirmed by law enforcement.